The PIK3R1 Polyclonal Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to GRB1, and PIK3R1. This antibody recognizes Human, Mouse, and Rat antigen. The PIK3R1 Polyclonal Antibody has been validated for the following applications: ELISA, and Immunohistochemistry.
Description
Phosphatidylinositol 3-kinase phosphorylates the inositol ring of phosphatidylinositol at the 3-prime position. The enzyme comprises a 110 kD catalytic subunit and a regulatory subunit of either 85, 55, or 50 kD. This gene encodes the 85 kD regulatory subunit. Phosphatidylinositol 3-kinase plays an important role in the metabolic actions of insulin, and a mutation in this gene has been associated with insulin resistance. Alternative splicing of this gene results in four transcript variants encoding different isoforms